Drug Intermediates

Approx. Rs 230 / KgGet Latest Price

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We are among the distinguished names in the industry for supplying and trading Para Toluene Sulphonyl Chloride. The offered chemical compound is used as an intermediate for formulation of various drugs in the pharmaceutical industry. It is precise in terms of composition, has uniform sized particles and stable pH level as well. This compound is processed as per stringent parameters of quality control.

4-Toluenesulfonyl chloride is an organic compound with the formula CH???C???H???SO???Cl. This white, malodorous solid is a reagent widely used in organic synthesis. Abbreviated TsCl or TosCl, it is a derivative of toluene and contains a sulfonyl chloride functional group.


Features:

• Precise composition
• Hygienic
• Effective

Approx. Rs 8,000 / KgGet Latest Price

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Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
Etoricoxib is a member of the class of bipyridines that is 2,3'-bipyridine which is substituted at the 3, 5, and 6' positions by 4-(methylsulfonyl)phenyl, chlorine, and methyl groups, respectively. It has a role as a cyclooxygenase 2 inhibitor and a non-steroidal anti-inflammatory drug. It is a sulfone, a member of bipyridines and an organochlorine compound.
Etoricoxib is a selective COX-2 inhibitor from Merck & Co. Currently it is approved in more than 80 countries worldwide but not in the US, where the Food and Drug Administration has required additional safety and efficacy data for etoricoxib before it will issue approval.
Molar mass: 358.842 g/molElimination half-life: 22 hoursFormula: C₁₈H₁₅ClN₂O₂SMetabolism: Hepatic, CYP extensively involved (mainly CYP3A4)ATC code: M01AH05 (WHO)